Reticulocyte haem synthesis in occupational exposure to trinitrotoluene.
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چکیده
منابع مشابه
Haem inhibits iron uptake subsequent to endocytosis of transferrin in reticulocytes.
Haem controls the rate of haem synthesis in erythroid cells by inhibiting iron incorporation from transferrin. The present results indicate that haem primarily inhibits the release of iron from transferrin subsequent to transferrin endocytosis and that the inhibition of transferrin endocytosis caused by relatively high concentrations of haem is a secondary effect. Low concentrations of haem (10...
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Background: Trinitrotoluene (TNT) is one of the most well-known and oldest explosive agents. In the recent decade, bioenvironmental, biochemical, and biological effects of TNT exposure have been more in the spotlight. In this study, we aimed to evaluate spirometric parameters in workers of a TNT factory exposed to TNT and other related fumes and dusts compared with the unexposed controls. Metho...
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A routine procedure for the monitoring of occupational exposure to 2,4,6-trinitrotoluene (TNT) based on the semiquantitative determination of 4-amino-2,6-dinitrotoluene (4A2,6-DNT) in urine samples by gas chromatography (GC-MS) was developed. For calibration purposes, a standard sample of 4-amino-4,6-dinitrotoluene was prepared. Urine samples were collected from munition workers in a military p...
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عنوان ژورنال:
- British journal of industrial medicine
دوره 42 5 شماره
صفحات -
تاریخ انتشار 1985